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avatar for Christian Melander

Christian Melander

NC State University
Howard Schaeffer Distinguished Professor
Yarbrough Drive, Raleigh, NC 27695-8204
Background
  • Postdoctoral, The Scripps Research Institute, 2002 - 2004
  • Lead Scientist, Xencor, 2001-2002
  • Postdoctoral, California Institute of Technology,1998 - 2001
  • Ph. D., Organic Chemistry, Columbia University, 1998
  • M. Phil., Organic Chemistry, Columbia University, 1998
  • M. A., Organic Chemistry, Columbia University, 1995
  • B. S., Chemistry, University of California, Davis, 1994
Awards
  • NIH Postdoctoral Fellowship, 1999-2000
  • Chemistry-Biology Research Training Grant, NIH, 1995-1998
Christian Melander received a B.S. in Chemistry with departmental honors from UC Davis in 1994 where he worked under the direction of Professor Mark Kurth developing combinatorial approaches to small molecule libraries. He subsequently received a Ph.D. in organic chemistry, supported by an NIH chemistry and biology-training grant, studying with Professor David Horne at Columbia University where he investigated the catalytic potential of nucleic acid bases. From 1998-2001 Christian was an NIH postdoctoral scholar at Caltech under the direction of Professor Peter Dervan studying the sequence-specific recognition of DNA with pyrrole/imidazole polyamides. Christian then directed the organic synthesis department at Xencor, Inc. in Monrovia, CA as a Lead Scientist from February of 2001 until September of 2002. He returned to academic research as a Research Associate at The Scripps Research Institute in the laboratory of Professor Joel Gottesfeld in the Department of Molecular Biology from 2002-2004. At Scripps, Christian utilized pyrrole/imidazole polyamides to explore potential therapeutics for both colon cancer and Friedrich’s ataxia. In July of 2004, Christian accepted a position as an Assistant Professor at North Carolina State University in the Department of Chemistry, in August, 2010 was promoted to Associate Professor with tenure and in August of 2013 promoted to Full Professor. At NCSU, Christian’s research is focused on 1) defining small molecules that control bacterial behavior and 2) small molecule-coated nanoparticles that have antibacterial and antiviral properties. During his independent career, Christian has received the Sigma Xi faculty research award, the NCSU Entrepreneur of the Year award, the Industrial Innovation Award from the Southeastern ACS, was named a University Faculty Scholar from 2014-2018, and was awarded the Howard J. Schaeffer Professor of Chemistry in 2014.