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Thursday, August 27 • 4:00pm - 4:20pm
[0033] Heterocycle Synthesis from Quinols

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A variety of substituted 1-hydroxyacridones were synthesized in a one-pot carbamation/Michael addition/Claisen Condensation/decarboxylation cascade in two steps from commercial phenols in good to excellent yields (41-96%). Furthermore, synthesis of 4-hydoxycarbazoles from quinols was realized through a carbamation/Michael/enolate-aryl coupling/aromatization sequence. This methodology was also applied to a short total synthesis of carbazomycin B.


ST Lecturers
avatar for Jing Wu

Jing Wu

Graduate Student, | Hunter College, | New York, NY



Thursday August 27, 2015 4:00pm - 4:20pm
Girvetz 2112