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Thursday, August 27 • 11:20am - 12:20pm
[0155] E. C. Taylor Senior Award: Synthesis of Heterocycles By Cyclizations and Functionalizations

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In general, the synthesis of complex biologically active molecules are problematic but the problems, encountered during the syntheses, can be a good source of inspiration to develop methods. One major challenge is the design of concise strategies as well as chemoselective and efficient methods that rapidly lead to the skeleton framework of natural and/or biologically active heterocyclic compounds.

In this context, we have explored the construction of heterocycles using catalytic reactions involving transition metal catalysts and heat. Metal catalysts and heat can induce rearrangements, cyclizations, functionalizations which can be highly diastereoselective and enantioselective if a chiral ligand is added in the reaction media. These reactions and their applications to the synthesis of heterocyclic natural and non-natural products will be presented

Plenaries and Awardees
avatar for Janine Cossy

Janine Cossy

Professor, ESPCI
Professor Janine Cossy graduated from the University of Reims working under the supervision of Prof. Jean-Pierre Pète. After a postdoctoral stay with Prof. Barry Trost (1980-1982) at the University of Wisconsin, she returned to Reims where she became Director of Research of the CNRS... Read More →

Thursday August 27, 2015 11:20am - 12:20pm
Corwin Pavilion